Cultural Exchange in addition to the positive side still contains many conflicting ideas, viewpoints and content...Obviously the national response to globalization of culture is not the same. It is confirmed that, who benefit most from the process of globalization of culture is humanity. However, there are still many who lose out. It is the economic force, different religions, for selfish reasons or somehow backward, to maintain power and its benefits by means of the old rule. The world today is witnessing ethnic conflicts, religious conflicts lasting Middle East, Gulf, many countries in Asia, Africa, or the more you...The protest in East Timor extreme applications such as terrorism, ethnic conflict and religious conflict so reflects backward, culturally conservative part of the human race and its repercussions and political economy. That fact is inevitable. When the culture of mutual penetration, the common values ​​entering the individual values​​, individual areas will cause reactions including radical reactions. Due to the unique political, geographical characteristics that are always different reaction and if they become overly extreme reaction. But despite the extreme reactions that humanity is still not back down on the trend of cultural globalization. These extreme reactions that will eventually take away along with the benefits that they receive, in the research process, while enjoying the fruits of the common culture of humanity. Understand that these extreme reactions are inevitable human progress to be vigilant and cooperate together to find solutions against such negative manifestations. That solution is the increase of knowledge , building civil society, the rule of law, building a global control mechanism to bring democracy, equality, together supporting economic development, reduce conflict between peoples and regions.